Prompt: simple explanation of the image (try first without extra keywords)
Negative: "cartoon, painting, illustration, (worst quality, low quality, normal quality:2)"
Steps: >20 (if image has errors or artefacts use higher Steps)
CFG Scale: 5 (higher config scale can lose realism, depends on prompt, sampler and Steps)
Sampler: Any Sampler (SDE, DPM-Sampler will result in more realism)
Size: 512x768 or 768x512